fludrocortisone will minimize the level or result of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
In the United States, cinacalcet is indicated to the treatment of secondary hyperparathyroidism in individuals with Persistent kidney disorder on dialysis and hypercalcemia in people with parathyroid carcinoma.
Comply with all Instructions on the prescription label. Your medical professional may well at times modify your dose to make sure you get the best outcomes. Will not use cinacalcet in larger sized or smaller amounts or for lengthier than advised.
zafirlukast will boost the level or effect of cinacalcet by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
C: Use with caution if Rewards outweigh challenges. Animal studies present danger and human reports not accessible or neither animal nor human experiments done.
This medicine could possibly be employed for other purposes; request your health care provider or pharmacist For those who have questions.
Drug conversation overview Concurrent administration with calcium-reducing medicines which includes other calcium-sensing receptor agonists could result in significant hypocalcemia; intently check serum calcium in sufferers acquiring the drug therapy and concomitant therapies identified PDF Rotation to reduce serum calcium levels
mavorixafor will enhance the amount or outcome of cinacalcet by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a robust CYP2D6 inhibitor) is contraindicated with medicines which are highly depending on CYP2D6 for clearance.
It's not a complete list of Unintended effects and also other really serious Unintended effects or medical problems that could come about due to the use of this drug.
Monitor Closely (1)eliglustat raises levels of cinacalcet by impacting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Check Intently. Observe therapeutic drug concentrations, as indicated, or consider decreasing the dosage in the concomitant drug and titrate to medical result.
In individuals at risk, getting therapy, who build hypocalcemia, carefully keep an eye on corrected serum calcium and QT interval
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lumefantrine will minimize the level or impact of cinacalcet by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Cinacalcet is partly metabolized by CYP3A4. Dose adjustment of Sensipar can be required if a affected individual initiates or discontinues therapy with a powerful CYP3A4 inhibitor (e.